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Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

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Effects of ageing on articular cartilage homeostasis

Tirzepatide is a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus under the brand name Mounjaro and for chronic weight management under the brand name Zepbound

10.1111/1759-7714.13925 60 GuoY.TongY.ZhuH.XiaoY.GuoH.ShangL.et al (2021b)

The healing process following the injury is accompanied by an increase in vascularization