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have anti-inflammatory, anti-ischemic and anti-fibrotic effects and inhibit myocardiocyte apoptosis.29,32,42 More recently, it has been reported that they also reduce epicardial fat.43 They also inhibit platelet aggregation and thrombosis.44 In the lungs, rGLP-1 activation conferred protection against lipopolysaccharide-induced acute lung injury.45 In adipose tissue they favor adipocyte differentiation, decreases lipid deposition in white fat and facilitate its conversion to brown fat, as well as thermogenesis and energy consumption29,32,4648

Figure 15: Photograph of Professor Roger Unger, credit The Lancet

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The programs on this list all include physician oversight