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Treated animals showed improved load-to-failure, reduced inflammatory infiltrates, and enhanced tendon-to-bone healing
The treatment usually begins with a low initial dose, which is then gradually increased over several weeks
UGT1A4 appears to be the principle isoenzyme involved in the reaction
The hospitalization rate was statistically significantly higher than that of other GLP-1RA, but the mortality was low (2.46%), indicating that semaglutide had a high risk of AKI, but the severity may be relatively low