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SCFAs have a very short half-life and are rapidly metabolized by colonocytes or the liver before reaching the systemic circulation or the heart

Topical forms of HRT, such as oestrogen gels or suppositories, are often preferred as their absorption is not affected by gastric emptying

But smaller volumes are harder to measure accurately on an insulin syringe

The mixture was evaporated until the volume was reduced to 3 to 5 mL

Nutr Metab Cardiovasc Dis 19:291302

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