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2022, Feb, 17;602(7897):38385 Briggs A, Vassall A

The short-term IP dosing triggered DNA repair and inflammatory TNF-alpha/NF-kB pathways in females, which are canonical responses to metabolic stress or tissue injury

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The innovation pipeline is now dominated by a critical debate surrounding dual agonists versus single agonists, with multi-receptor compounds demonstrating superior clinical outcomes

, Kim1 expression increased with higher doses of sulfasalazine (Supplemental Figure 6), suggesting a dose-dependent nephrotoxic effect