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Additionally, old DCs express lower levels of CCR7 and CCR9, resulting in decreased migratory activity, as demonstrated in studies on aged mice [255]

This Review focuses on the contributions of the following factors: age-related inflammation (also referred to as 'inflammaging')

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An important limitation of the DSIP literature is that much of the human research was published decades ago, primarily during the 1980s and early 1990s