The comparator groups differed among studies, with some employing placebo controls (e.g., PIONEER-6, Gerstein 2019), others using active comparators such as sitagliptin, glimepiride, DPP-4 inhibitors, or SGLT2 inhibitors, and some utilizing standard care or intensive lifestyle interventions as the control
Probiotic strains such as Lactobacillus, Akkermansia muciniphila , and Bifidobacterium have been shown to improve gut barrier integrity, modulate immune responses, and influence hepatocellular fat metabolism
Glucose-induced cAMP elevation in -cells involves amplification of constitutive and glucagon-activated GLP-1 receptor signalling
During pregnancy, ensuring that the mother and unborn baby both get enough vitamin B12, which is important for brain development and other functions
Improvement in glycaemic parameters using SGLT-2 inhibitor and GLP-1 agonist in combination in an adolescent with diabetes mellitus and Prader-Willi syndrome: a case report
- Especially helpful if you're incorporating more activity as part of your wellness journey