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Highlights from the July 2024 study include: Our main finding is that prescribed semaglutide is associated with an increased risk of NAION. Patients with diabetes who took semaglutide were more than four times more likely to develop NAION than those on other medications

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Severe calorie restriction in perimenopause can actually make things worse by: Further decreasing metabolic rate (adaptive thermogenesis) Increasing cortisol (chronic stress response) Promoting muscle loss over fat loss Disrupting already-irregular hormone patterns Ive seen women eating 1200 calories and doing intense cardio six days per week, completely exhausted and still gaining weight

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PMID: 29138605