Recommended monitoring protocol: Baseline: Full thyroid panel (TSH, free T4, free T3, TPO antibodies, thyroglobulin antibodies) plus thyroid ultrasound before starting GLP-1 therapy 6-8 weeks after starting GLP-1: Recheck TSH and free T4
SchilperoortMvanDam ADHoekeGShabalinaIGOkoloAHanyalogluACet al
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Keywords: semaglutide, GLP-1, once weekly, type 2 diabetes, ethinylestradiol, levonorgestrel Glucagon-like peptide-1 (GLP-1) is a gut-derived incretin hormone that potentiates insulin secretion, inhibits glucagon secretion, reduces appetite, and delays the rate of gastric emptying in response to food intake
These are the operational targets we design for
The liver benefits appear to result largely from weight reduction and improved metabolic health rather than direct liver-specific effects, which is why NICE recommends lifestyle modification as first-line treatment for fatty liver disease
