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Single S2 may occur in: a) If one of the semilunar valves is missing, as in pulmonary or aortic valve atresia and truncus arteriosus

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The rate-limiting step of the salvage pathway is catalyzed by NAMPT and requires PRPP as a cosubstrate, which is mostly supplied by the PPP pathway in cancer cells

doi: 10.1016/S0378-1119(01)00803-4 48 CherryADPiantadosiCA