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The washed beads were mixed with 0.5 mL (10 fold dilution of initial concentration) purified human recombinant Trx1 protein (0.85 mg), diluted to 8 mL with 50 mM HEPES buffer (pH 7.5) and supplemented with 1 mM TCEP

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Th17 cells in primary Sjogren's syndrome negatively correlate with increased Roseburia and Coprococcus

There is no standardized timeframe

A Phase 1 registry record has no posted efficacy result, and a small uncontrolled knee-pain report does not establish benefit