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High doses of Thiamine are reported to help calm nervous or over excitable horses

For more information about these drugs, including details about their uses, see this Contrave overview and this Wegovy overview

Vital for activation of nerves and movement of muscles, it influences blood pressure, sleep, pain and relaxation

When comparing whey protein isolate vs concentrate for weight loss, whey concentrate is best

Think of it as a protective shield against the wear and tear of time

The bottom line: If building muscle is the primary goal, a GLP-1 medication in the context of a deep caloric deficit is not the ideal environment