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En outre, le maintien dun taux stable de glutathion sur le long terme protge contre le dclin cognitif li l'ge mais aussi contre la dgradation du systme osseux (ostoporose)

Oxidative stress may also modulate MMP expression by activation of the rat sarcoma viral oncogene (RAS), or direct activation of the MAPK family members extracellular-signal regulated kinase 1/2 (ERK1/2), p38, and JNK, or inactivation of phosphatases that regulate these proteins [160]

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When ARA-290 binds to this assembled receptor, it triggers a cascade of protective effects

Progress in Neuropsychopharmacology & Biological Psychiatry