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as an oral dietary supplement under DSHEAno FDA pre-market approval required for products using the grandfathered ingredient

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The small-study effect was evaluated by the formal tests of Eggers and Beggs

(This amount is about 100 times higher than the RDA due to the fact that only about 1% of ingested B12 from supplements is absorbed.) All vegans should take 250 mcg per day of a B12 supplement

3cg are the simple linear regression lines (Extended Data Table 2)