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Appropriate uses of Pepto-Bismol during Wegovy treatment: Occasional diarrhoea: If you experience mild, intermittent loose stools, Pepto-Bismol may provide symptomatic relief

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The leading molecular mechanisms underlying these effects are believed to involve the downregulation of the Notch 1 and TGF-2/SMAD3 signaling pathways, concomitant with the upregulation of TGF-3

That means we may see orforglipron available sometime in 2026 or later