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Furthermore, quercetin counteracts ferroptosis under inflammatory conditions by modulating the IL-6/STAT3 pathway to regulate ferritinophagy and promote cellular iron export (79)

These findings, along with the fact that the lung can normally maintain GSH for long periods even with the oxidant burden of CS, lend credence to the theory that disease symptoms could arise when adaptive responses fail or are dysfunctional

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Treatment If the tumor is localized to an extremity, treatment involves surgical resection

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