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People with diabetes, particularly severe diabetes, tend to lose less weight with GLP-1s than people without diabetes, so microdosing is less likely to be as effective, though their dose should only be increased as they tolerate it. George said that in her professional opinion, microdosing is a potential option for patients with smaller amounts of weight to lose or as a bridge to start, or wean off, regular GLP-1 medications
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Science 383 , 830832 (2024)
Their fat loss is not typical
The goal is to preserve lean muscle mass and bone density while on the drug and to build habits that will maintain health if patients stop taking the medication
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