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While hes optimistic about GLP-1s' broader health benefits, he said high hopes have been dashed before once scientists move beyond early, observational findings

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Glucagon-like peptide 1 (GLP-1) agonists not only exert a beneficial systemic effect, but also cross the blood-brain barrier (Kastin et al., 2002

This process does not involve changes in gene expression at first, but results in secretion failure due to physical consumption

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The tumor suppressor P53 limits ferroptosis by blocking DPP4 activity