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Activation of glucagon-like peptide-1 receptor in microglia exerts protective effects against sepsis-induced encephalopathy via attenuating endoplasmic reticulum stress-associated inflammation and apoptosis in a mouse model of sepsis

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The study, published in "Frontiers in Psychiatry", found that patients taking glucagon-like peptide-1 (GLP-1) medications including widely used drugs such as Ozempic were substantially less likely to develop alcohol, opioid, nicotine and cocaine use disorders than similar patients who were not prescribed the medications