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McCoy, MD, MS, associate professor of medicine in the University of Maryland School of Medicine and director of the center for population health in the University of Maryland Institute for Health Computing, said the increased risk early during therapy is likely due to health care professionals being more vigilant with thyroid cancer screening when a person starts GLP-1 therapy

Investigations suggest that peptides interacting with these receptors might influence neuroendocrine communication networks that coordinate hormonal rhythms, metabolic responses, and circadian regulation

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It can be used long-term if effective and well tolerated.