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Beatty et al., 2017

Individuals with specific genetic profiles may exhibit heightened insulin response, warranting faster medication de-escalation and more frequent blood glucose monitoring

Elevated creatinine levels are also observed with high-protein diets

In terms of mechanisms, tesofensine inhibits the uptake of serotonin, noradrenaline, and dopamine, leading to appetite suppression and increased feelings of fullness

Highlights Persistent mitochondrial and immune alterations are observed across multiple tissues in PCS-associated datasets

This comprehensive understanding of TSSs role in improving metabolic health enlightens us about its potential benefits in combating various health conditions