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Leucovorin is a folate-based medication traditionally used in medicine (for example, as a rescue drug with certain chemotherapies), and now its being studied for autism

C., Bustamante, S., Najib, N., Diwan, A., Jayasena, T., Chowdhury, N

2003 Oct;56(5):270-4

Expression of the cancer stem cell markers CD44 and CD133 in colorectal cancer: An immunohistochemical staining analysis

As an extension of the above, the brains high metabolic rate and oxygen consumption make it vulnerable to oxidative stress, which can lead to aging and neurodegenerative diseases like Alzheimers and Parkinsons Disease

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