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The SELECT trial demonstrated a 20% reduction in major adverse cardiovascular events (MACE), marking a significant advancement in cardiometabolic care

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6 In contrast, Yoshida and colleagues found through a meta-analysis of 4 CVOTsincluding trials that specifically showed cardiovascular benefit of GLP-1RAs and excluding trials testing off-market GLP-1RAsthat GLP-1RA was associated with retinopathy complications after 52 weeks on the drug

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