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However, as prescription of semaglutide and similar medications escalated, anecdotal reports of reduced alcohol use became very common, and suggested the potential of these more potent therapies for treatment of alcohol use disorder. While the findings are promising, the researchers still need to determine exactly how semaglutide reduces alcohol cravings

Their rationale is that radical surgery may be overtreatment because it carries no survival advantage for stage II or III patients

doi: 10.1056/NEJMoa2206038 104 GarveyWTFriasJPJastreboffAMLe RouxCWSattarNAizenbergDet al

Case reports can identify plausible risk but cannot estimate incidence