MSC-Exos, however, persistently modulate the cellular microenvironment, promoting tissue repair alongside ferroptosis suppression [104]
IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a synthetic analog of human insulin-like growth factor-1 (IGF-1) with structural modifications that distinguish it from the endogenous peptide
Ali M, Martinez M, Parekh N
Also in 2005, the mRNA-sequence of the equine psoriasin (a calcium-binding protein of the S100-protein family with antimicrobial activities [38]) was described and the gene was mapped to equine chromosome 5 [39]
Cost: Injections and IV drips can be expensive and impractical
Advances such as CRISPR and surface modifications allow for the customization of Exos for tailored therapies, aligning with the goals of precision medicine [243, 244]