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But it reminds us that obesity has many causes and very likely will require many different therapeutic options

doi: 10.1007/s00125-013-2841-0 32 CalannaSChristensenMHolstJJLaferrreBGluudLLVilsbllTet al

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Beyond weight loss, the expanding therapeutic landscape of GLP-1 agonists now includes cardiovascular risk reduction, peripheral artery disease management, and active clinical trials for neurodegenerative disorders and substance use disorderswith over 15 global trials underway for the latter indication alone

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