Her last recorded weight was 149 kg (BMI 70.9 kg/m 2 ), with WC of 140 cm and WHR of 0.96
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Behavioral study also demonstrated that modulating AMPA/kainite, but not NMDA, receptor-mediated glutamatergic neurotransmission within VTA is involved in GLP-1-induced intake-suppressive effects (Mietlicki-Baase et al., 2013)
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Patients with CS show phenotypical characteristics including moon face, facial plethora, striae rubrae, supraclavicular and dorsal fat pads (86) and several comorbidities including DM, visceral obesity dyslipidaemia, cardiovascular disease, osteoporosis and vertebral fractures, infections and neuropsychiatric disorders, which can sometimes persist even after the disease is cured and contribute to increased mortality, compared to the general population (87, 88)
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