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The column was equilibrated and run with 20 mM phosphate buffer (pH 8.0), containing 150 mM NaCl and 2 mM GSH with a flow rate of 0.5 mL/min at 25C

Plainsboro, NJ: Novo Nordisk Inc

Together, these results show that MT prevents cell proliferation in high TRIP13-expressing NSCLC cell lines

310 Similar effects are observed after transgenic deletion of Ccl2 specifically from astrocytes, which showed little effects early in EAE but demonstrated that astrocyte Ccl2 sustains disease symptoms and inflammation during chronic EAE, making it a therapeutic target

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In summary, recent CV outcomes trials with GLP-1RAs have shown promising benefits in CV care of T2D patients, and GLP-1RAs have been accordingly listed as a second line therapy in T2D patients with established atherosclerotic CV disease, alongside SGLT2 inhibitors [5, 6]