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The LC-MS was operated using a top 3 data-dependent acquisition (DDA) experiment that involved a full MS scan in the mass range of m/z 58870 at 35,000 resolution, followed by MS/MS scans at 17,500 resolution, isolation window of m/z 1.2 and collision energy of 28

The study also found that only 13.2% of participants experienced gastrointestinal side effects after switching, and just 2% discontinued tirzepatide due to adverse events

Common Side Effects Nausea Stomach discomfort Mild headache Diarrhea Dizziness These side effects are generally mild and temporary

Total weight loss by week twelve usually reaches 8% to 10% of starting body weight