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Insulin sensitization therapy Metformin Metformin, the most widely used insulin sensitizer for PCOS, reduces hepatic glucose production, inhibits gluconeogenesis and adipogenesis, improves peripheral tissue sensitivity to insulin, and prevents excessive insulin activity in the ovary [153]
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Novo Nordisks Wegovy is available as multiple-dose pre-filled pens that deliver a preset dose for once-weekly dosing, while Ozempic is available as multiple-dose pre-filled pens for single-patient use, designed for once-weekly dosing
Sallinen P, Saarela S, Ilves M, Vakkuri O, Leppluoto J (2005) The expression of MT1 and MT2 melatonin receptor mRNA in several rat tissues
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