391 GLP-1 and GLP-1 analogs exert their effects on food intake and body weight through a myriad of neural substrates, encompassing several hypothalamic nuclei (including the arcuate nucleus of the hypothalamus, periventricular hypothalamus, and lateral hypothalamic area), hindbrain nuclei (such as the parabrachial nucleus and medial nucleus tractus solitarius), the ventral subregion of the hippocampus (vHP), and nuclei embedded within the mesolimbic reward circuitry (including the ventral tegmental area, VTA, and nucleus accumbens, NAc)
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Reviewers often point to the brand's minimalistic yet informed structure as a breath of fresh air in a market overwhelmed by overly complex solutions
Johnson RK, Appel LJ, Brands M, Howard BV, Lefevre M, Lustig RH, Sacks F, Steffen LM, Wylie-Rosett J: Dietary sugars intake and cardiovascular health: a scientific statement from the American Heart Association
Both medications carry a risk for rare but serious side effects, including pancreatitis and possible thyroid C-cell tumors (seen mainly in animal studies)
On average, patients can lose up to 15% of their body weight within 3 months when combined with a balanced diet and lifestyle changes