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Dihexa demonstrates synaptogenic activity approximately seven orders of magnitude more potent than brain-derived neurotrophic factor (BDNF) in preclinical models

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UBX0101 This molecule is a p53/MDM2 inhibitor used as a senolytic to treat osteoarthritis (OA)

Die eNOS-Aktivierung geschieht ber die Akt-Kinase und ist mit der VEGFR2-Signalisierung (Vascular Endothelial Growth Factor Receptor 2) verbunden

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In addition, both TTP and gAgAP downregulated transcription levels of angiotensin II receptor type 1 ( agtr1 ) and miR-132/-212, with TTP producing a comparable reduction in agtr1 to captopril and a significant decrease in miR-132/-212 expression