5.3 Ketogenic diets A ketogenic diet (KD) is a diet high in fat, low in carbohydrates, and adequate in protein (Figure 3C), which results in a reduction in glucose supply and enhancement of ketogenesis (121)
Influenza infection resulted in increased inflammation and epithelial cell injury in our murine model, leading to increased morbidity and mortality
however, no significant changes were observed in LDL or total cholesterol.28 A 2022 meta-analysis focusing on adults with metabolic syndrome risk factors reached similar conclusions, noting modest reductions in LDL cholesterol and systolic blood pressure but overall marginal changes in total cholesterol.29 A broader 2024 review summarizing human and preclinical data suggests that astaxanthin may enhance insulin sensitivity and glucose uptake while supporting lipid metabolism and antioxidant balance, though these findings are based on limited trials and changes in biomarkers.30 These effects are thought to involve activation of Nrf2, a cellular pathway that turns on the bodys own antioxidant defenses, and improved mitochondrial energy metabolism, which may help regulate oxidative stress
His clinical interests include dermatologic conditions, anti-aging therapeutics, and the translation of dermatology research into accessible patient guidance
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