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Introduction The term oxidative stress (OS) applies when increased amounts of reactive oxygen species (ROS) surpass the antioxidant (AOX) capacity that naturally offers the protective balance ( Hence, AOX therapy to enhance fertility by protecting against the harmful effects of ROS is theoretically feasible

doi: 10.1186/s10194-019-0993-0, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 2.Wu JW, Yang CP

2003 Jan;327(1-2):187-8

Mechanistically, a microglial inflammation-oxidative stress feedforward loop perpetuates injury: Activated microglia secrete neurotoxins, impairing neuronal mitochondrial function and antioxidant capacity (such as GPX4), thus increasing ROS leakage

Alzheimer's patients saw their cognitive function improve by 29% (ADAS-Cog scores) after 84 days of CMA treatment