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Despite its clinical success, bortezomib is limited by acquired resistance and adverse effects, including peripheral neuropathy and hematologic toxicity

Vitamin B 12 deficiency in the elderly

Chloroplast-localized iron superoxide dismutases FSD2 and FSD3 are functionally distinct in Arabidopsis

doi:10.1017/S0029665112000092 25 26 27 28 29 30 31 32 33 34 35 36 Ravi M, Miller AH, Michopoulos V

Schloot, et al., 'Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial', Lancet Diabetes Endocrinol

Collectively, all GLP-1 receptor agonists, including native GLP-1, peptides, and small molecule GLP-1 receptor agonists, stabilize the binding pocket of the GLP-1 receptor in a similar fashion, which induces the TM helices 6 kink, a distinctive feature of the active state of the class B1 GPCR