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Your healthcare provider will determine the optimal duration based on your progress, tolerance, and goals
Theres no universal rule for how frequently you should check, but your healthcare provider can guide you based on your specific health situation
Additionally, while Health Canada has not approved indication for weight loss, employers are getting requests from employees
Clinicians should: Assess baseline HbA1c and current glycemic control before discontinuation Implement or intensify alternative therapies (metformin, SGLT2 inhibitors, or other agents) before or concurrent with tirzepatide cessation Increase home glucose monitoring frequency for several weeks post-discontinuation Schedule follow-up to evaluate metabolic stability Special consideration for insulin or sulfonylurea users : Patients taking these medications alongside tirzepatide may need proactive dose adjustments when stopping tirzepatide to prevent hypoglycemia
Patients and physicians are both learning of various benefits and off-label indications for this group of medications, referred to as glucagon-like peptide-1 receptor agonists (GLP-1 RAs)
Gonzalez-Mariscal L, Tapia R, Chamorro D (2008) Crosstalk of tight junction components with signaling pathways
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