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Recommended Retatrutide Dosing Schedule and Titration Guidance In Phase 2 trials, retatrutide was titrated from a starting dose of 0.5 mg once weekly, with incremental increases at approximately four-weekly intervals to maintenance doses of 4 mg, 8 mg, or 12 mg

Typically the few days following my injection, Im not overly hungry, so I lean on higher nutrient-dense foods

Lastly, no significant main effects or interactions were found for CXCL1 in this area (all p 0.269)

Katagiri K et al

The dosage chart is well-established, tested across thousands of patients in the SURMOUNT trial series , and refined to minimize side effects while maximizing weight loss outcomes

doi: 10.1016/j.ebiom.2025.106119