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Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors

Takahashi T, Shiraishi A

Its not clear if this comes on suddenly or gradually

doi:[10.1111/dom.15728] Heather J Leidy, Peter M Clifton, Arne Astrup, Thomas P Wycherley, Margriet S Westerterp-Plantenga, Natalie D Luscombe-Marsh, Stephen C Woods, Richard D Mattes, The role of protein in weight loss and maintenance234, The American Journal of Clinical Nutrition, Volume 101, Issue 6, 2015, Pages 1320S-1329S,ISSN 0002-9165, Institute of Medicine