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Ethics approval and consent to participate All relevant ethics documents were approved by the Institutional Research Ethics Committee of Nanjing Medical University (for clinical patients) and Nanjing University (for mice)

Spicy Foods Chili and heavily seasoned dishes can irritate your stomach lining and worsen heartburn, so if you are sensitive, ease in with some mild spices and test your tolerance gradually

Data availability All the data and material were available

Additionally, while AOD-9604 demonstrated excellent safety in the studied populations, individual medical histories may reveal contraindications or concerns requiring careful evaluation

Nutritional support No nutrition guidance, meal plans, or dietary resources are included

Semaglutide is the newest FDA-approved treatment for weight loss