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Compound degradation risk over months

Pekovic-Vaughan et al

Chronic calcitriol supplementation improves the inflammatory profiles of circulating monocytes and the associated intestinal/adipose tissue alteration in a diet-induced steatohepatitis rat model

These abnormalities can lead to perturbed lipid peroxidation and expression of neurotrophic factors which ultimately cause degenerative nerve function

Of interest, in the study design, the company states that included individuals had a flexible dosing protocol [125], which could have accounted for not meeting the desired 25% body weight reduction target

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