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These interventions carry no pharmacological risk and have well-established long-term benefits for metabolic health, cardiovascular risk reduction, and psychological wellbeing

It plays an essential role in protecting cells from oxidative damage, eliminating toxins, supporting liver function, and regulating melanin production

Ascorbic Acid: Both are antioxidants, but GHK-Cu also stimulates ECM and healing, while vitamin C focuses on collagen synthesis and brightening

In chronic obstructive pulmonary disease, a disease with increased prevalence in aged individuals, zinc deficiency hinders the clearance of apoptotic epithelial cells by alveolar macrophages, contributing to persistent inflammation [234]

In severe cases, arrhythmias can be life-threatening and require immediate medical attention

Non-randomized studies were assessed with the Risk of Bias in Non-randomized Studies of Interventions tool (ROBINS-I) [8]