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J Biomed Res 2013;27:254-71

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In fact, brain is the organ containing the largest amount of DHA in the whole organism, and it seems that it was selected soon in the evolution of the cephalization process of vertebrates to provide a special biochemical microenvironment to nerve cell membranes, especially during the massive accretion in the evolution of primate brains (Crawford et al., sn-2 position of glycerophospholipids (mainly phosphatidylethanolamine and phosphatidylserine, the most abundant phospholipids in nerve cells) and is largely determinant of the structural and physicochemical properties of plasma membrane

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