But given that Novo Nordisk and Eli Lilly have announced their desire to make these blockbuster drugs for their shareholders, and that they are actively working to increase the market for them to be as large as possible, I think it does mean that these drugs should be highly scrutinized and that emphasis should be placed on giving clear, accurate informed consent, including and especially for the larger weight loss doses
The average patient age was 75 years (range: 23 to 102 years)
[12] This mechanism slows gastric emptying (most notably early in therapy), prolongs feelings of fullness, and reduces hunger signals in the brain , leading to decreased food intake and subsequent weight loss
Consequently, they may exhibit undefined or broad specificity and relatively high equilibrium dissociation constant (Kd) values for their targets [442]
These features offer convenience and possibly better adherence
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