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Parts of the brain that drive eating behaviors overlap extensively with the drive to use alcohol or other substances, explained Lorenzo Leggio, M.D., Ph.D., and Leandro Vendruscolo, Pharm.D., Ph.D., two of the senior authors of the study

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Furthermore, throughout the treatment, patients may experience other symptoms, such as nausea, vomiting, lack of appetite, hormonal fluctuations, sleep disturbances, alterations in taste, and changes in skin color (Rana et al., 2017

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Bydureon, the once-weekly formulation, has already successfully finished phase 3 human studies, demonstrating an ability to provide greater blood glucose control (determined by A1c) and similar weight loss as Byetta but with reduced rates for nausea and vomiting (common side effects associated with GLP-1 agonists)

Moreover, NSAIDs, known for their toxicity in various organs, remained limited to their damaging effect on the stomach mucosa