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Insurance companies are probably paying ~$3-5K/year (after deductible usage) for these medications, and pharma is receiving anywhere from 40-70% of the list
mRNA capping: biological functions and applications
These drugs work by mimicking the action of naturally occurring GLP-1, an incretin hormone that stimulates insulin secretion in response to food intake, suppresses glucagon release, and slows gastric emptying
When GLP-1 agonists reach these receptors, they reduce microglial activation and dampen neuroinflammatory signals
It has entered GLP-1 with a liraglutide launch and has two GLP-1 supply contracts
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Gallbladder problems: Right upper abdominal pain, fever, yellowing of skin or eyes (jaundice), or clay-colored stools may indicate cholecystitis or cholelithiasis
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