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Induction in certain studies was mainly mediated by Nrf-2 agonists, such as curcumin and resveratrol (62,63)

For all subsequent analyses, samples were resuspended in 5% sodium dodecyl sulfate (SDS) 50 mM triethylammonium bicarbonate (TEAB), enough to cover the pellet, placed in 95 C for 10 min and thereafter clarified by centrifuging at 10,000 g for 10 min at room temperature

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For a 165-pound person, that would translate to about 75 mg, which is far above typical human protocols

Glutathione and cold sores Cold sores are primarily caused by HSV-1, a virus that induces oxidative stress upon infection and generates ROS, which can damage cellular components and exacerbate the inflammatory response