The goal is to develop these predictors into strategies for risk-stratified treatment and follow-up recommendations to reduce adverse events, improve quality of life, and ultimately reduce mortality
They are usually used only for a short period of time, since prolonged NSAID use can lead to unwanted effects on the body like stomach ulcers and bleeding within the gastrointestinal tract
Histopathological examination is the key and would show granular deposits of yellow-brown pigment and no inflammation
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In addition, clinical trials for 77A/G polymorphism of MMP-13 and risk for developing knee OA are currently being conducted in the Greek population [66]
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