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WT1 has been shown to bind to the IGF-1R promoter and to suppress activity (Werner et al, 1995)

Furthermore, the low consumption of vegetables and fruits causes a lack of exogenous antioxidants, while an excessive intake of animal proteins (mainly red and processed meat) and fats has been associated with increased oxidants, increasing the risk of immune-mediated disorders, including autoimmune thyroid diseases [186, 187]

The 5mC and 5hmC immunoprecipitation signals were determined using gene-specific primers (Supplementary Table 1)