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Intranasal formulations of fentanyl, midazolam, dexmedetomidine, and ketamine are emerging as quick, practical options for procedural sedation and analgesia, but more research is needed

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Dumanovi J, Nepovimova E, Nati M et al (2021) The significance of reactive oxygen species and antioxidant defense system in plants: a concise overview

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However, these side effects can often be managed or minimized with proper monitoring and dosage adjustments