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Anti-diabetic medications such as Metformin: This anti-diabetic medicine can decrease absorption of vitamin B12, potentially reducing the effectiveness of Walcobal Injection

Patients on metformin, PPIs, or with liver/kidney disease should consult a provider before starting

The Closest Human Evidence and It Was Negative There is no human Dihexa trial, but the same HGF/c-Met drug program did reach human testing through Athira Pharma's fosgonimeton (ATH-1017)

Similarly, some research suggests BPC-157 can promote new blood cell growth, reduce inflammation and heal tissue in rats

Thus, we recommend to regularly assess cognitive function among PwPD, test Vit B12 serum levels along with Hcy and MMA levels

*Correspondence: Chen Chen, [email protected] Guo, [email protected] These authors have contributed equally to this work This article was submitted to Molecular Signalling and Pathways, a section of the journal Frontiers in Molecular Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers